Maciek Sasinowski earned a Ph.D. in computational plasma physics from The College of William and Mary. Prior to his work in bioinformatics, he developed the delta-f Monte Carlo algorithm used to predict the behavior of thermonuclear fusion plasmas. The algorithm constitutes a 10,000-fold improvement in computational speed over traditional Monte Carlo algorithms used in the field.

In 1996, Dr. Sasinowski was appointed to establish the Bioinformatics Center at the Clemson University Genomics Institute. There, he attracted a staff of twenty scientists and technicians and directed the bioinformatics infrastructure to support the research and production work of 85 scientists.

In 1998, Dr. Sasinowski founded INCOGEN.  He was one of the founding members of the Integrated Informatics Infrastructure Consortium (I3C) and continues to play leading roles in community efforts such as the National Cancer Institute Cancer Biomedical Informatics Grid (caBIG).  In 2001, Dr. Sasinowski was chosen by the Genome Technology magazine as one of the 15 most influential people in the field of genomics under the age of 30.  More recently, he was voted among the top three most influential people in genomics tool development in an Internet survey conducted by GenomeWeb.  Dr. Sasinowski is a member of the Governor's Technology Transition Policy Committee and serves as the Chair of the Board of Directors of the Virginia Biotechnology Association (VABio).